Preheat your oven to 350°F (175°C).
In a large mixing bowl, combine cooked spaghetti, shredded chicken, cream of chicken soup, milk, and garlic powder.
Stir in the frozen mixed vegetables, paprika, salt, and pepper until incorporated.
Transfer the mixture into a greased 9x13 inch baking dish, spreading it evenly.
Sprinkle shredded cheddar cheese on top of the casserole mix.
Top with breadcrumbs for added crunch and flavor.
Bake in the preheated oven for 30-35 minutes or until heated through and the top is golden brown.
Remove from the oven and let it cool for a few minutes before serving.