Cook the macaroni according to package instructions.
Preheat the oven to 350°F (175°C).
In a saucepan, melt the butter over medium heat.
Add flour to the melted butter and whisk to create a roux.
Gradually add the milk while whisking continuously to avoid lumps.
Add mustard powder, garlic powder, salt, and pepper; continue whisking until thickened.
Remove from heat and gradually stir in the cheeses until melted.
Combine the drained macaroni with the cheese sauce, stirring to coat evenly.
In a separate bowl, mix panko breadcrumbs with olive oil.
Transfer the mac and cheese to a baking dish and top with the panko mixture.
Bake for 20–25 minutes, or until the top is golden brown and bubbly.